ADOA is the most common hereditary optic atrophy disease. Learn about current research and clinical trials to help find a cure.
There is currently no cure for Autosomal Dominant Optic Atrophy (ADOA). However, great strides have recently been made in regards to research to find a cure. Click on the links below to learn what's in the pipeline.
Since this disease deteriorates the optic nerve, visual aids such as glasses or contacts will not help improve one's vision impairment. Management generally consists of regular eye exams, including measurement of visual acuity, color vision, visual fields and optical coherence tomography (OCT). Low-vision aids in individuals with severely decreased visual acuity can be helpful. (7)
Click the link to help find a doctor in your area who is knowledgeable about ADOA
While ADOA is currently identified as untreatable there is one study that showed improved visual acuity and function with the use of Idebenone therapy. Idebenone is a synthetic analog of coenzyme Q10. It has powerful antioxidant properties that help prevent free radical damage to our cells. It has shown to be effective for those with cardiac and mitochondrial issues. The study was conducted on seven patients with Dominant Optic Atrophy who carry the OPA1 gene mutation. Results showed, for the first time, some improvement in visual function after Idebenone therapy. Read more about Idebenone Treatment in Patients with OPA1-mutant dominant optic atrophy.